| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 28.09.21 20:45 | Cardiff City | West Bromwich Albion | 0:4 |
| 28.09.21 20:45 | Huddersfield Town | Blackburn Rovers | 3:2 |
| 28.09.21 20:45 | Hull City A.F.C. | FC Blackpool | 1:1 |
| 28.09.21 20:45 | FC Middlesbrough | Sheffield United | 2:0 |
| 28.09.21 20:45 | Preston North End | FC Stoke City | 1:1 |
| 28.09.21 20:45 | Queens Park Rangers | Birmingham City | 2:0 |
| 29.09.21 20:45 | FC Fulham | Swansea City | 3:1 |
| 29.09.21 20:45 | FC Barnsley | Nottingham Forest | 1:3 |
| 29.09.21 20:45 | Derby County | FC Reading | 1:0 |
| 29.09.21 20:45 | Luton Town | Coventry City | 5:0 |
| 29.09.21 20:45 | FC Millwall | Bristol City | 1:0 |
| 29.09.21 20:45 | Peterborough United | AFC Bournemouth | 0:0 |