| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 19.10.21 20:45 | Bristol City | Nottingham Forest | 1:2 |
| 19.10.21 20:45 | Derby County | Luton Town | 2:2 |
| 19.10.21 20:45 | Queens Park Rangers | Blackburn Rovers | 1:0 |
| 19.10.21 20:45 | Sheffield United | FC Millwall | 1:2 |
| 19.10.21 20:45 | FC Stoke City | AFC Bournemouth | 0:1 |
| 20.10.21 20:45 | FC Fulham | Cardiff City | 2:0 |
| 20.10.21 20:45 | Swansea City | West Bromwich Albion | 2:1 |
| 20.10.21 20:45 | Huddersfield Town | Birmingham City | 0:0 |
| 20.10.21 20:45 | Hull City A.F.C. | Peterborough United | 1:2 |
| 20.10.21 20:45 | FC Middlesbrough | FC Barnsley | 2:0 |
| 20.10.21 20:45 | Preston North End | Coventry City | 2:1 |
| 20.10.21 21:00 | FC Reading | FC Blackpool | 2:3 |