| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 22.02.22 20:45 | FC Middlesbrough | West Bromwich Albion | 2:1 |
| 22.02.22 20:45 | Preston North End | Nottingham Forest | 0:0 |
| 22.02.22 20:45 | Bristol City | Coventry City | 1:2 |
| 22.02.22 20:45 | Hull City A.F.C. | FC Barnsley | 0:2 |
| 22.02.22 21:00 | FC Reading | Birmingham City | 2:1 |
| 23.02.22 20:45 | Derby County | FC Millwall | 1:2 |
| 23.02.22 20:45 | FC Fulham | Peterborough United | 2:1 |
| 23.02.22 20:45 | Queens Park Rangers | FC Blackpool | 2:1 |
| 23.02.22 20:45 | Sheffield United | Blackburn Rovers | 1:0 |
| 23.02.22 20:45 | Huddersfield Town | Cardiff City | 2:1 |
| 23.02.22 20:45 | FC Stoke City | Luton Town | 1:2 |
| 26.04.22 20:45 | Swansea City | AFC Bournemouth | 3:3 |