| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 04.03.22 20:45 | Sheffield United | Nottingham Forest | 1:1 |
| 04.03.22 20:45 | Huddersfield Town | Peterborough United | 3:0 |
| 05.03.22 13:30 | FC Fulham | Blackburn Rovers | 2:0 |
| 05.03.22 16:00 | Bristol City | Birmingham City | 1:2 |
| 05.03.22 16:00 | Derby County | FC Barnsley | 2:0 |
| 05.03.22 16:00 | Hull City A.F.C. | West Bromwich Albion | 0:2 |
| 05.03.22 16:00 | FC Middlesbrough | Luton Town | 2:1 |
| 05.03.22 16:00 | Preston North End | AFC Bournemouth | 2:1 |
| 05.03.22 16:00 | FC Reading | FC Millwall | 0:1 |
| 05.03.22 16:00 | Queens Park Rangers | Cardiff City | 1:2 |
| 05.03.22 16:00 | Swansea City | Coventry City | 3:1 |
| 05.03.22 16:00 | FC Stoke City | FC Blackpool | 0:1 |