| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 10.09.21 21:00 | Birmingham City | Derby County | 2:0 |
| 11.09.21 16:00 | Swansea City | Hull City A.F.C. | 0:0 |
| 11.09.21 16:00 | FC Stoke City | Huddersfield Town | 2:1 |
| 11.09.21 16:00 | West Bromwich Albion | FC Millwall | 1:1 |
| 11.09.21 16:00 | Blackburn Rovers | Luton Town | 2:2 |
| 11.09.21 16:00 | FC Blackpool | FC Fulham | 1:0 |
| 11.09.21 16:00 | AFC Bournemouth | FC Barnsley | 3:0 |
| 11.09.21 16:00 | Bristol City | Preston North End | 0:0 |
| 11.09.21 16:00 | Coventry City | FC Middlesbrough | 2:0 |
| 11.09.21 16:00 | Sheffield United | Peterborough United | 6:2 |
| 11.09.21 16:00 | FC Reading | Queens Park Rangers | 3:3 |
| 12.09.21 15:30 | Nottingham Forest | Cardiff City | 1:2 |