| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 18.09.21 13:30 | Hull City A.F.C. | Sheffield United | 1:3 |
| 18.09.21 16:00 | Cardiff City | AFC Bournemouth | 0:1 |
| 18.09.21 16:00 | Luton Town | Swansea City | 3:3 |
| 18.09.21 16:00 | Huddersfield Town | Nottingham Forest | 0:2 |
| 18.09.21 16:00 | FC Middlesbrough | FC Blackpool | 1:2 |
| 18.09.21 16:00 | FC Millwall | Coventry City | 1:1 |
| 18.09.21 16:00 | Peterborough United | Birmingham City | 3:0 |
| 18.09.21 16:00 | Preston North End | West Bromwich Albion | 1:1 |
| 18.09.21 16:00 | Queens Park Rangers | Bristol City | 1:2 |
| 18.09.21 16:00 | FC Barnsley | Blackburn Rovers | 0:0 |
| 18.09.21 16:00 | Derby County | FC Stoke City | 2:1 |
| 18.09.21 16:00 | FC Fulham | FC Reading | 1:2 |