| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 26.01.21 19:00 | Real Valladolid | UD Levante | 2:4 |
| 26.01.21 21:00 | Real Betis Sevilla | Real Sociedad | 3:1p.d. |
| 26.01.21 21:00 | FC Girona | FC Villarreal | 0:1 |
| 27.01.21 19:00 | FC Sevilla | FC Valencia | 3:0 |
| 27.01.21 21:00 | UD Almeria | CA Osasuna | 5:4p.k. |
| 27.01.21 21:00 | Rayo Vallecano | FC Barcelona | 1:2 |
| 28.01.21 19:00 | CD Artistico Navalcarnero | FC Granada | 0:6 |
| 28.01.21 21:00 | CD Alcoyano | Athletic Bilbao | 1:2 |