| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 22.01.21 20:45 | Chorley FC | Wolverhampton Wanderers | 0:1 |
| 23.01.21 13:15 | FC Southampton | FC Arsenal | 1:0 |
| 23.01.21 16:00 | Sheffield United | Plymouth Argyle | 2:1 |
| 23.01.21 16:00 | Swansea City | Nottingham Forest | 5:1 |
| 23.01.21 16:00 | Brighton and Hove Albion | FC Blackpool | 2:1 |
| 23.01.21 16:00 | FC Millwall | Bristol City | 0:3 |
| 23.01.21 16:00 | FC Barnsley | Norwich City | 1:0 |
| 23.01.21 16:00 | West Ham United | Doncaster Rovers | 4:0 |
| 23.01.21 18:30 | Cheltenham Town | Manchester City | 1:3 |
| 24.01.21 13:05 | FC Chelsea | Luton Town | 3:1 |
| 24.01.21 15:30 | FC Fulham | FC Burnley | 0:3 |
| 24.01.21 15:30 | Brentford FC | Leicester City | 1:3 |
| 24.01.21 18:00 | Manchester United | Liverpool FC | 3:2 |
| 24.01.21 21:00 | FC Everton | Sheffield Wednesday | 3:0 |
| 25.01.21 20:45 | Wycombe Wanderers | Tottenham Hotspur | 1:4 |
| 26.01.21 20:00 | AFC Bournemouth | Crawley Town | 2:1 |