| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 22.10.17 22:00 | New York City FC | Columbus Crew | 2:2 |
| 22.10.17 22:00 | Portland Timbers | Vancouver Whitecaps | 2:1 |
| 22.10.17 22:00 | Houston Dynamo | Chicago Fire | 3:0 |
| 22.10.17 22:00 | D.C. United | New York Red Bulls | 1:2 |
| 22.10.17 22:00 | FC Dallas | Los Angeles Galaxy | 5:1 |
| 22.10.17 22:00 | Seattle Sounders | Colorado Rapids | 3:0 |
| 22.10.17 22:00 | Real Salt Lake | Sporting Kansas City | 2:1 |
| 22.10.17 22:00 | CF Montreal | New England Revolution | 2:3 |
| 22.10.17 22:00 | Philadelphia Union | Orlando City | 6:1 |
| 22.10.17 22:00 | San Jose Earthquakes | Minnesota United FC | 3:2 |
| 22.10.17 22:00 | Atlanta United FC | Toronto FC | 2:2 |