| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 10.05.18 01:30 | Toronto FC | Seattle Sounders | 1:2 |
| 10.05.18 01:30 | Atlanta United FC | Sporting Kansas City | 0:2 |
| 10.05.18 01:30 | Columbus Crew | Philadelphia Union | 1:0 |
| 10.05.18 02:30 | Chicago Fire | CF Montreal | 1:0 |
| 10.05.18 04:00 | Los Angeles FC | Minnesota United FC | 2:0 |
| 12.05.18 04:30 | Vancouver Whitecaps | Houston Dynamo | 2:2 |
| 12.05.18 20:00 | Minnesota United FC | San Jose Earthquakes | 1:3 |
| 12.05.18 21:00 | CF Montreal | Philadelphia Union | 0:2 |
| 12.05.18 21:30 | FC Dallas | Los Angeles Galaxy | 3:2 |
| 13.05.18 01:30 | New England Revolution | Toronto FC | 3:2 |
| 13.05.18 01:30 | Columbus Crew | Chicago Fire | 3:0 |
| 13.05.18 03:00 | Real Salt Lake | D.C. United | 3:2 |
| 13.05.18 03:00 | Colorado Rapids | New York Red Bulls | 1:2 |
| 13.05.18 22:00 | Portland Timbers | Seattle Sounders | 1:0 |
| 14.05.18 00:00 | Orlando City | Atlanta United FC | 1:2 |
| 14.05.18 02:30 | Los Angeles FC | New York City FC | 2:2 |