| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 20.09.18 04:30 | Portland Timbers | Columbus Crew | 3:2 |
| 20.09.18 05:00 | Seattle Sounders | Philadelphia Union | 0:1 |
| 20.09.18 05:00 | San Jose Earthquakes | Atlanta United FC | 3:4 |
| 22.09.18 21:30 | Los Angeles FC | San Jose Earthquakes | 2:0 |
| 22.09.18 23:00 | New York Red Bulls | Toronto FC | 2:0 |
| 23.09.18 01:00 | Atlanta United FC | Real Salt Lake | 2:0 |
| 23.09.18 01:30 | New England Revolution | Chicago Fire | 2:2 |
| 23.09.18 01:30 | CF Montreal | New York City FC | 1:1 |
| 23.09.18 01:30 | Orlando City | Houston Dynamo | 0:0 |
| 23.09.18 01:30 | Columbus Crew | Colorado Rapids | 2:1 |
| 23.09.18 02:00 | Minnesota United FC | Portland Timbers | 3:2 |
| 23.09.18 19:00 | Philadelphia Union | Sporting Kansas City | 2:0 |
| 24.09.18 01:00 | Vancouver Whitecaps | FC Dallas | 1:2 |
| 24.09.18 01:00 | Los Angeles Galaxy | Seattle Sounders | 3:0 |