| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 06.10.18 21:00 | CF Montreal | Columbus Crew | 3:0 |
| 06.10.18 21:30 | Atlanta United FC | New England Revolution | 2:1 |
| 06.10.18 23:00 | Toronto FC | Vancouver Whitecaps | 1:2 |
| 07.10.18 01:30 | Philadelphia Union | Minnesota United FC | 5:1 |
| 07.10.18 02:00 | FC Dallas | Orlando City | 2:0 |
| 07.10.18 02:30 | Sporting Kansas City | Los Angeles Galaxy | 1:1 |
| 07.10.18 03:00 | Colorado Rapids | Los Angeles FC | 0:3 |
| 07.10.18 03:30 | Real Salt Lake | Portland Timbers | 1:4 |
| 07.10.18 04:30 | San Jose Earthquakes | New York Red Bulls | 1:3 |
| 07.10.18 19:00 | D.C. United | Chicago Fire | 2:1 |
| 09.10.18 04:30 | Seattle Sounders | Houston Dynamo | 4:1 |