| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 13.10.18 04:00 | Los Angeles FC | Houston Dynamo | 4:2 |
| 18.10.18 01:30 | Orlando City | Seattle Sounders | 1:2 |
| 18.10.18 01:30 | D.C. United | Toronto FC | 1:0 |
| 18.10.18 04:00 | Vancouver Whitecaps | Sporting Kansas City | 1:4 |
| 19.10.18 03:00 | Real Salt Lake | New England Revolution | 4:1 |
| 21.10.18 21:00 | D.C. United | New York City FC | 3:1 |
| 21.10.18 21:00 | Atlanta United FC | Chicago Fire | 2:1 |
| 21.10.18 21:00 | CF Montreal | Toronto FC | 2:0 |
| 21.10.18 21:00 | Orlando City | Columbus Crew | 2:1 |
| 21.10.18 23:00 | FC Dallas | Sporting Kansas City | 0:3 |
| 21.10.18 23:00 | Houston Dynamo | Seattle Sounders | 2:3 |
| 21.10.18 23:00 | San Jose Earthquakes | Colorado Rapids | 0:0 |
| 21.10.18 23:00 | Los Angeles FC | Vancouver Whitecaps | 2:2 |
| 21.10.18 23:00 | Portland Timbers | Real Salt Lake | 3:0 |
| 21.10.18 23:00 | Minnesota United FC | Los Angeles Galaxy | 1:3 |
| 28.10.18 21:30 | New York City FC | Philadelphia Union | 3:1 |