| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 12.04.18 01:00 | New York City FC | Real Salt Lake | 4:0 |
| 14.04.18 02:00 | Philadelphia Union | Orlando City | 0:2 |
| 14.04.18 04:00 | Vancouver Whitecaps | Los Angeles FC | 0:2 |
| 14.04.18 19:00 | New York Red Bulls | CF Montreal | 3:1 |
| 14.04.18 21:00 | Colorado Rapids | Toronto FC | 2:0 |
| 14.04.18 21:30 | Chicago Fire | Los Angeles Galaxy | 0:1 |
| 15.04.18 01:00 | D.C. United | Columbus Crew | 1:0 |
| 15.04.18 01:30 | New England Revolution | FC Dallas | 0:1 |
| 15.04.18 04:30 | San Jose Earthquakes | Houston Dynamo | 2:2 |
| 15.04.18 04:30 | Portland Timbers | Minnesota United FC | 3:2 |
| 15.04.18 22:00 | Sporting Kansas City | Seattle Sounders | 2:2 |
| 16.04.18 00:00 | Atlanta United FC | New York City FC | 2:2 |