| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 25.04.19 01:00 | New York City FC | Chicago Fire | 1:0 |
| 25.04.19 01:30 | New England Revolution | CF Montreal | 0:3 |
| 25.04.19 01:30 | Columbus Crew | D.C. United | 0:1 |
| 25.04.19 02:00 | Minnesota United FC | Los Angeles Galaxy | 0:0 |
| 25.04.19 04:30 | Seattle Sounders | San Jose Earthquakes | 2:2 |
| 27.04.19 19:00 | New York City FC | Orlando City | 1:1 |
| 27.04.19 21:00 | Toronto FC | Portland Timbers | 1:2 |
| 27.04.19 21:30 | FC Dallas | San Jose Earthquakes | 0:0 |
| 27.04.19 23:00 | Vancouver Whitecaps | Philadelphia Union | 1:1 |
| 28.04.19 00:00 | Atlanta United FC | Colorado Rapids | 1:0 |
| 28.04.19 01:00 | New York Red Bulls | Cincinnati FC | 1:0 |
| 28.04.19 02:30 | Sporting Kansas City | New England Revolution | 4:4 |
| 28.04.19 02:30 | Houston Dynamo | Columbus Crew | 2:0 |
| 28.04.19 18:30 | CF Montreal | Chicago Fire | 1:0 |
| 28.04.19 19:30 | Minnesota United FC | D.C. United | 1:0 |
| 28.04.19 21:30 | Seattle Sounders | Los Angeles FC | 1:1 |
| 29.04.19 02:00 | Los Angeles Galaxy | Real Salt Lake | 2:1 |