| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 23.09.20 23:00 | New England Revolution | CF Montreal | 3:1 |
| 24.09.20 01:00 | New York City FC | Toronto FC | 0:1 |
| 24.09.20 01:00 | Atlanta United FC | FC Dallas | 1:0 |
| 24.09.20 01:30 | Columbus Crew | Minnesota United FC | 2:1 |
| 24.09.20 01:30 | Sporting Kansas City | Orlando City | 1:2 |
| 24.09.20 01:30 | Cincinnati FC | Philadelphia Union | 0:0 |
| 24.09.20 01:30 | Chicago Fire | Houston Dynamo | 4:0 |
| 24.09.20 02:00 | Inter Miami CF | New York Red Bulls | 1:4 |
| 24.09.20 02:30 | Nashville SC | D.C. United | 1:0 |
| 24.09.20 03:00 | Colorado Rapids | San Jose Earthquakes | 5:0 |
| 24.09.20 03:30 | Real Salt Lake | Los Angeles Galaxy | 2:0 |
| 24.09.20 04:00 | Portland Timbers | Seattle Sounders | 1:0 |
| 24.09.20 04:30 | Los Angeles FC | Vancouver Whitecaps | 6:0 |