| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 26.09.20 21:30 | Nashville SC | Houston Dynamo | 1:1 |
| 27.09.20 01:00 | New York City FC | Cincinnati FC | 4:0 |
| 28.09.20 01:00 | D.C. United | New England Revolution | 0:2 |
| 28.09.20 01:00 | New York Red Bulls | CF Montreal | 4:1 |
| 28.09.20 01:30 | Toronto FC | Columbus Crew | 3:1 |
| 28.09.20 01:30 | Chicago Fire | Atlanta United FC | 2:0 |
| 28.09.20 01:30 | Philadelphia Union | Inter Miami CF | 3:0 |
| 28.09.20 02:00 | Minnesota United FC | Real Salt Lake | 0:0 |
| 28.09.20 02:30 | FC Dallas | Orlando City | 0:0 |
| 28.09.20 04:00 | Vancouver Whitecaps | Portland Timbers | 0:1 |
| 28.09.20 04:30 | Los Angeles Galaxy | Seattle Sounders | 1:3 |
| 28.09.20 04:30 | Los Angeles FC | San Jose Earthquakes | 1:2 |