| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 07.10.20 02:30 | Nashville SC | Minnesota United FC | 0:0 |
| 08.10.20 01:00 | New York Red Bulls | Inter Miami CF | 1:2 |
| 08.10.20 01:00 | Atlanta United FC | Orlando City | 0:0 |
| 08.10.20 01:30 | Philadelphia Union | Cincinnati FC | 3:0 |
| 08.10.20 01:30 | New England Revolution | Toronto FC | 0:1 |
| 08.10.20 01:30 | Columbus Crew | CF Montreal | 1:2 |
| 08.10.20 02:00 | Houston Dynamo | FC Dallas | 2:0 |
| 08.10.20 02:00 | New York City FC | D.C. United | 4:1 |
| 08.10.20 02:30 | Sporting Kansas City | Chicago Fire | 1:0 |
| 08.10.20 04:00 | Seattle Sounders | Real Salt Lake | 2:1 |
| 08.10.20 04:30 | San Jose Earthquakes | Vancouver Whitecaps | 3:0 |
| 08.10.20 04:30 | Los Angeles Galaxy | Portland Timbers | 3:6 |