| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 15.10.20 01:30 | Toronto FC | New York Red Bulls | 1:1 |
| 15.10.20 01:30 | Orlando City | New York City FC | 1:1 |
| 15.10.20 01:30 | CF Montreal | New England Revolution | 2:3 |
| 15.10.20 01:30 | Cincinnati FC | Columbus Crew | 2:1 |
| 15.10.20 02:00 | Inter Miami CF | Atlanta United FC | 1:1 |
| 15.10.20 02:00 | Houston Dynamo | Nashville SC | 1:3 |
| 15.10.20 02:00 | D.C. United | Philadelphia Union | 2:2 |
| 15.10.20 02:30 | FC Dallas | Sporting Kansas City | 1:0 |
| 15.10.20 03:30 | Real Salt Lake | Portland Timbers | 2:1 |
| 15.10.20 04:00 | Vancouver Whitecaps | Los Angeles FC | 2:1 |
| 15.10.20 04:30 | Los Angeles Galaxy | San Jose Earthquakes | 0:4 |
| 05.11.20 02:00 | Minnesota United FC | Chicago Fire | 2:2 |