| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 23.10.20 04:30 | Seattle Sounders | Portland Timbers | 1:1 |
| 24.10.20 03:50 | Nashville SC | New England Revolution | 1:1 |
| 24.10.20 21:30 | Inter Miami CF | Orlando City | 2:1 |
| 24.10.20 22:00 | Atlanta United FC | D.C. United | 1:2 |
| 25.10.20 01:30 | Philadelphia Union | Toronto FC | 5:0 |
| 25.10.20 01:30 | New York City FC | CF Montreal | 3:1 |
| 25.10.20 01:30 | Chicago Fire | New York Red Bulls | 2:2 |
| 25.10.20 01:30 | Cincinnati FC | Minnesota United FC | 0:1 |
| 25.10.20 02:00 | Houston Dynamo | Columbus Crew | 1:1 |
| 25.10.20 02:30 | Sporting Kansas City | Colorado Rapids | 4:0 |
| 25.10.20 02:30 | Real Salt Lake | FC Dallas | 0:0 |
| 25.10.20 03:00 | Vancouver Whitecaps | San Jose Earthquakes | 2:1 |
| 25.10.20 20:30 | Los Angeles FC | Los Angeles Galaxy | 2:0 |