| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 06.09.20 02:00 | Orlando City | Atlanta United FC | 1:1 |
| 06.09.20 02:00 | Houston Dynamo | Sporting Kansas City | 2:1 |
| 06.09.20 03:30 | Vancouver Whitecaps | Toronto FC | 3:2 |
| 06.09.20 04:30 | San Jose Earthquakes | Colorado Rapids | 1:1 |
| 07.09.20 01:00 | D.C. United | New York City FC | 0:0 |
| 07.09.20 01:00 | New York Red Bulls | Philadelphia Union | 0:3 |
| 07.09.20 01:30 | Columbus Crew | Cincinnati FC | 3:0 |
| 07.09.20 01:30 | Chicago Fire | New England Revolution | 1:2 |
| 07.09.20 02:00 | Minnesota United FC | Real Salt Lake | 4:0 |
| 07.09.20 03:45 | Inter Miami CF | Nashville SC | 0:0 |
| 07.09.20 04:00 | Seattle Sounders | Portland Timbers | 1:2 |
| 07.09.20 04:30 | Los Angeles Galaxy | Los Angeles FC | 3:0 |