| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 12.06.21 21:00 | Sporting Kansas City | Austin FC | 1:1 |
| 17.07.21 23:00 | Atlanta United FC | New England Revolution | 0:1 |
| 18.07.21 01:30 | CF Montreal | Cincinnati FC | 5:4 |
| 18.07.21 01:30 | Toronto FC | Orlando City | 1:1 |
| 18.07.21 01:30 | Philadelphia Union | D.C. United | 2:1 |
| 18.07.21 01:30 | Columbus Crew | New York City FC | 2:1 |
| 18.07.21 02:30 | Nashville SC | Chicago Fire | 5:1 |
| 18.07.21 03:00 | Colorado Rapids | San Jose Earthquakes | 1:1 |
| 18.07.21 04:00 | Vancouver Whitecaps | Los Angeles Galaxy | 2:1 |
| 18.07.21 04:30 | Los Angeles FC | Real Salt Lake | 2:1 |
| 18.07.21 04:30 | Portland Timbers | FC Dallas | 1:0 |
| 18.07.21 20:00 | Minnesota United FC | Seattle Sounders | 1:0 |
| 10.10.21 00:00 | New York Red Bulls | Inter Miami CF | 1:0 |