| Termin | Gospodarz | Gość | Wynik |
|---|---|---|---|
| 24.09.21 02:20 | Houston Texans | Carolina Panthers | 9:24 |
| 26.09.21 19:00 | Jacksonville Jaguars | Arizona Cardinals | 19:31 |
| 26.09.21 19:00 | New England Patriots | New Orleans Saints | 13:28 |
| 26.09.21 19:00 | Detroit Lions | Baltimore Ravens | 17:19 |
| 26.09.21 19:00 | Cleveland Browns | Chicago Bears | 26:6 |
| 26.09.21 19:00 | Pittsburgh Steelers | Cincinnati Bengals | 10:24 |
| 26.09.21 19:00 | Kansas City Chiefs | Los Angeles Chargers | 24:30 |
| 26.09.21 19:00 | New York Giants | Atlanta Falcons | 14:17 |
| 26.09.21 19:00 | Tennessee Titans | Indianapolis Colts | 25:16 |
| 26.09.21 19:00 | Buffalo Bills | Washington Football Team | 43:21 |
| 26.09.21 22:05 | Las Vegas Raiders | Miami Dolphins | 31:28OT |
| 26.09.21 22:05 | Denver Broncos | New York Jets | 26:0 |
| 26.09.21 22:25 | Los Angeles Rams | Tampa Bay Buccaneers | 34:24 |
| 26.09.21 22:25 | Minnesota Vikings | Seattle Seahawks | 30:17 |
| 27.09.21 02:20 | San Francisco 49ers | Green Bay Packers | 28:30 |
| 28.09.21 02:15 | Dallas Cowboys | Philadelphia Eagles | 41:21 |